Sporadic inclusion body myositis (sIBM) presents with a characteristic clinical phenotype of slow-onset weakness and atrophy, affecting proximal and distal limb muscles and facial and pharyngeal ...

Exposures to silica dust, solvents or heavy metals increase the likelihood of developing various forms of myositis, ...

Inclusion Body Myositis- Features asymmetric muscle weakness and distinct histopathologic findings, such as rimmed vacuoles. Drug-induced Myopathies- Commonly associated with medications like ...

New research examining the skeletal muscle cells of patients with inclusion body myositis (IBM) has revealed that the nucleic acid-binding protein TDP-43, which is normally restricted to the ...

Myopathic (myo = muscle, pathy = disease) conditions can include polymyositis, dermatomyositis, inclusion body myositis, and various myopathies due to metabolic, congenital, and endocrine causes.

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sIBM is a complex disorder, the underlying cause of which is unclear. The observation that the intact muscle fibers are invaded by T lymphocytes, whereas the vacuolated fibers lack T-cell ...