Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, researchers understand that the specialized, differentiated cell types of the adult ...

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

7 Proper regulation of splicing factors ensures accurate tissue-specific gene expression and cell differentiation. Alternative splicing is conserved throughout the phylogenetic tree with the same ...

This spatial differentiation may be driven by local ... Neşet Özel et al, Does a cell's gene expression always reflect its function?, Nature (2025). DOI: 10.1038/d41586-025-00088-1 ...

Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene ...

Our blood consists of many cell types that develop through different stages from a precursor type – the blood stem cell. An ...

When cells express specific genes that characterise ... coding and transferring biological information though its unique structure. Gene expression Gene expression is the process by which specific ...

In particular, we are interested in understanding how changes in metabolite availability shape the chromatin landscape to influence gene expression programs that control cell survival, growth and ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Single-cell multiomic analyses reveal known and new genes and pathways involved in the development of germ cells and provide a discovery platform for the scientific community.