Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...

In nature, green fluorescent proteins give fluorescent ... information about the deep structure of protein biology emerges in the network." Scientists already modify natural proteins and engineer ...

Fluorescent proteins have come along way since the discovery ... “The truncated phytochrome crystal structure was available, which facilitated protein engineering,” explains Xiaokun Shu ...

The crystal structure of GFP ... With the cloning of new fluorescent proteins from species other than jellyfish came the discovery of a red fluorescent protein — the holy grail of fluorescence ...

From growth hormones to cancer drugs, small molecules play a crucial role in our health. Monitoring them is essential to ...

GFP had a cyclized portion in its structure, and many people thought that such a ... With a background in dye chemistry, Tsien saw the value a fluorescent protein could offer biological research.

Unlike fluorescent proteins, luciferases don’t need an excitation light ... of this superfamily share a pocket that could hold onto a synthetic luciferin. With a structure that could bind to a ...

The team engineered special "pockets" within a protein cage structure called ferritin ... When specific fluorescent ligands bind to these pockets, they trigger what could be described as a ...

Single-molecule imaging, a technique that uses fluorescent markers to track proteins with precision ... they identified its structure using mass spectrometry and nuclear magnetic resonance ...

To prevent this, cells have developed a sophisticated system to mark unwanted proteins for degradation with a small protein called ubiquitin. Ubiquitin chains Ubiquitin is a cellular tag that marks ...