For a time, however, it appeared that fluorescent protein engineering had hit a 'yellow' wall in efforts to red-shift fluorescence emission. Fortuitously, this barrier had already been surmounted ...

Proteins play a key role in the life sciences — from basic research and biotechnological applications to the development and ...

It works by using UV light to excite proteins from harmful microbes and then detecting the resulting fluorescence. In ...

1 This was the first example of a light-activated protein, which they called a photoprotein. I wanted to have a tool like this. I thought this would be wonderful. —Martin Chalfie, Columbia University ...

Glioblastoma stem cells with fluorescent labeling for prion protein (red), CD44 protein (green), and cell nucleus (blue) ...

The issue of photobleaching—the loss of fluorescence upon prolonged light exposure—has made it difficult to track proteins inside cells or monitor intricate biological processes over extended ...

Genes have to be expressed in the right place, at the time, and at the right levels. Scientists wanted to know more about how ...

such as labeled proteins inside cells. The microscope combines polarized fluorescence technology, a valuable tool for measuring the orientation of molecules, with a dual-view light sheet ...