Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, researchers understand that the specialized, differentiated cell types of the adult ...

Our blood consists of many cell types that develop through different stages from a precursor type – the blood stem cell. An ...

CD34 and CD45 expression were analyzed via flow cytometry ... DLL4 and VCAM1 were used as a supportive environment to drive differentiation to NK cell lineage. Image Credit: ACROBiosystems Figure ...

Ten years of substantial work by Nathalie Labrecque's team at the Montreal Clinical Research Institute (IRCM) and the ...

The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

In particular, we are interested in understanding how changes in metabolite availability shape the chromatin landscape to influence gene expression programs that control cell survival, growth and ...

Obesity is a significant risk factor for various metabolic diseases and, in many cases, causes ectopic fat accumulation (i.e.

For the first time, researchers developed stem cell-derived pig retinal cells in comparison with human retinal cells, ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Bone morphogenetic proteins (BMPs) directly affect the osteogenic differentiation of stem cells and are integral to bone ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...