Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, researchers understand that the specialized, differentiated cell types of the adult ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

CD34 and CD45 expression were analyzed via flow cytometry ... DLL4 and VCAM1 were used as a supportive environment to drive differentiation to NK cell lineage. Image Credit: ACROBiosystems Figure ...

In particular, we are interested in understanding how changes in metabolite availability shape the chromatin landscape to influence gene expression programs that control cell survival, growth and ...

Researchers studying mesenchymal stem cells (MSCs) face significant challenges with traditional endpoint assays that provide only limited snapshots of the differentiation process. The inability to ...

Obesity is a significant risk factor for various metabolic diseases and, in many cases, causes ectopic fat accumulation (i.e.

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

Bone morphogenetic proteins (BMPs) directly affect the osteogenic differentiation of stem cells and are integral to bone ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative ...