He obliterated STING in a murine cell line and transfected the cells with different types of DNA. The team then collected the cytoplasm ... Laura is an Assistant Editor for The Scientist. She has a ...

DNA methylation is one of several epigenetic ... methylation near gene promoters varies considerably depending on cell type, with more methylation of promoters correlating with low or no ...

Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...

it is possible to optimize the values in the PWM such that the probability of binding to the known binding sites (versus the more abundant background DNA) is maximized. The optimal weight matrix ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding ... models across tissues and cell types. Aging involves complex cellular ...