It is one of a subset of tumors caused by faulty beta-catenin genes. These beta-catenin-activated tumors—which also include bowel, womb and melanoma skin cancer—all tend to have tumor ...

Jacob, professor of neuroscience at the School of Medicine and GSBS, and colleagues have been studying the CTNNB1 gene, which ...

The disclosure of a new candidate by Dewpoint Therapeutics Inc. was the latest in the percolating beta-catenin/Wnt space, where a handful of firms have been making progress.

Overholtzer et al. also noticed that before internalization, cells establish E-cadherin–beta-catenin-mediated adherens junctions and the compaction of these junctions appears to directly mediate ...