For example, the baculovirus genome can become unstable at high viral concentrations — and loss of the rep gene brings gene therapy vector production to a halt. This problem has been addressed ...

Based on the thorough experience and expertise in recombinant production, Sino Biological delivers high-purity and high-activity proteins with the baculovirus–insect cell protein expression platform.

These include MultiBac, a third-generation baculovirus expression vector system (BEVS) for eukaryotic multiprotein complex production. MultiBac is the major platform operated by the Berger laboratory.