New framework leverages 3D protein structures for systems-level analysis of cancer mutations
A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic ...
A new computational technique could make it easier to engineer useful proteins
This process has yielded optimized versions of many important proteins, including green fluorescent protein (GFP ... from DNA ...
pharmaphorum2d
AlphaFold 3 takes structure predictions well beyond proteins
The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships ... accuracy for the prediction of 3D protein structures, it offers a ...
Newly identified bacterial protein helps design cancer drug delivery system
A previously unknown protein in a family of bacteria found in soil and the human gut microbiome has been discovered—which ...
Nature2mon
Protein tags enhance GFP folding in eukaryotic cells
1 demonstrate that the fusion of the green fluorescent protein (GFP ... over mutagenesis methods of maintaining intact the protein structure under study.
Nature1mon
Training GFP to fold
A method to select for proteins that are highly efficient at folding yields 'superfolder' GFP, an optimized GFP for use in protein fusions. Fusion proteins are powerful tools for the elucidation ...