The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Now, AlphaFold 3 has widened the reach of the artificial ... which has just published a blog post on the update. “Experimental protein-structure prediction can take about the length of a PhD ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

Frank Uhlmann, a biochemist at the Francis Crick Institute in London, told Nature that he's been using the tool for ...

But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...

Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and ...

Because it only takes nanoseconds to microseconds for a protein to morph along its path to its final structure, the scientists needed to slow down the process during their analysis to be able to catch ...

Learn about our Editorial Policies. While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and ...